33 research outputs found

    Communications-Inspired Projection Design with Application to Compressive Sensing

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    We consider the recovery of an underlying signal x \in C^m based on projection measurements of the form y=Mx+w, where y \in C^l and w is measurement noise; we are interested in the case l < m. It is assumed that the signal model p(x) is known, and w CN(w;0,S_w), for known S_W. The objective is to design a projection matrix M \in C^(l x m) to maximize key information-theoretic quantities with operational significance, including the mutual information between the signal and the projections I(x;y) or the Renyi entropy of the projections h_a(y) (Shannon entropy is a special case). By capitalizing on explicit characterizations of the gradients of the information measures with respect to the projections matrix, where we also partially extend the well-known results of Palomar and Verdu from the mutual information to the Renyi entropy domain, we unveil the key operations carried out by the optimal projections designs: mode exposure and mode alignment. Experiments are considered for the case of compressive sensing (CS) applied to imagery. In this context, we provide a demonstration of the performance improvement possible through the application of the novel projection designs in relation to conventional ones, as well as justification for a fast online projections design method with which state-of-the-art adaptive CS signal recovery is achieved.Comment: 25 pages, 7 figures, parts of material published in IEEE ICASSP 2012, submitted to SIIM

    Advances in diffusion MRI acquisition and processing in the Human Connectome Project

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    The Human Connectome Project (HCP) is a collaborative 5-year effort to map human brain connections and their variability in healthy adults. A consortium of HCP investigators will study a population of 1200 healthy adults using multiple imaging modalities, along with extensive behavioral and genetic data. In this overview, we focus on diffusion MRI (dMRI) and the structural connectivity aspect of the project. We present recent advances in acquisition and processing that allow us to obtain very high-quality in-vivo MRI data, whilst enabling scanning of a very large number of subjects. These advances result from 2 years of intensive efforts in optimising many aspects of data acquisition and processing during the piloting phase of the project. The data quality and methods described here are representative of the datasets and processing pipelines that will be made freely available to the community at quarterly intervals, beginning in 2013

    Gender Differences in White Matter Microstructure

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    Sexual dimorphism in human brain structure is well recognised, but little is known about gender differences in white matter microstructure. We used diffusion tensor imaging to explore differences in fractional anisotropy (FA), an index of microstructural integrity.A whole brain analysis of 135 matched subjects (90 men and 45 women) using a 1.5 T scanner. A region of interest (ROI) analysis was used to confirm those results where proximity to CSF raised the possibility of partial-volume artefact.Men had higher fractional anisotropy (FA) in cerebellar white matter and in the left superior longitudinal fasciculus; women had higher FA in the corpus callosum, confirmed by ROI.The size of the differences was substantial--of the same order as that attributed to some pathology--suggesting gender may be a potentially significant confound in unbalanced clinical studies. There are several previous reports of difference in the corpus callosum, though they disagree on the direction of difference; our findings in the cerebellum and the superior longitudinal fasciculus have not previously been noted. The higher FA in women may reflect greater efficiency of a smaller corpus callosum. The relatively increased superior longitudinal fasciculus and cerebellar FA in men may reflect their increased language lateralisation and enhanced motor development, respectively

    Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data

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    The degree to which genetic factors influence brain connectivity is beginning to be understood. Large-scale efforts are underway to map the profile of genetic effects in various brain regions. The NIH-funded Human Connectome Project (HCP) is providing data valuable for analyzing the degree of genetic influence underlying brain connectivity revealed by state-of-the-art neuroimaging methods. We calculated the heritability of the fractional anisotropy (FA) measure derived from diffusion tensor imaging (DTI) reconstruction in 481 HCP subjects (194/287 M/F) consisting of 57/60 pairs of mono- and dizygotic twins, and 246 siblings. FA measurements were derived using (Enhancing NeuroImaging Genetics through Meta-Analysis) ENIGMA DTI protocols and heritability estimates were calculated using the SOLAR-Eclipse imaging genetic analysis package. We compared heritability estimates derived from HCP data to those publicly available through the ENIGMA-DTI consortium, which were pooled together from five-family based studies across the US, Europe, and Australia. FA measurements from the HCP cohort for eleven major white matter tracts were highly heritable (h2 = 0.53–0.90, p < 10− 5), and were significantly correlated with the joint-analytical estimates from the ENIGMA cohort on the tract and voxel-wise levels. The similarity in regional heritability suggests that the additive genetic contribution to white matter microstructure is consistent across populations and imaging acquisition parameters. It also suggests that the overarching genetic influence provides an opportunity to define a common genetic search space for future gene-discovery studies. Uniquely, the measurements of additive genetic contribution performed in this study can be repeated using online genetic analysis tools provided by the HCP ConnectomeDB web application

    Un algorithme de compression efficace de LUTs 3D couleur basé sur un schéma de diffusion anisotrope multi-échelle

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    International audience3D CLUTs (Color Look Up Tables) are popular digital models used in image and video processing for color grading, simulation of analog films, and more generally for the application of various colorimetric transformations. The large size of these models leads to data storage issues when trying to distribute them on a large scale. In this paper, a highly effective lossy compression technique for 3D CLUTs is proposed. It is based on a multi-scale anisotropic diffusion reconstruction scheme. Our method exhibits an average compression rate of more than 99%, while ensuring visually indistinguishable differences with the application of the original CLUTs .Les CLUTs 3D (Color Look Up Tables) sont des modèles numériques très utilisés en traitement d'images et de vidéos, pour l’étalonnage couleur, la simulation de films argentiques, et plus généralement pour l'application de transformées colorimétriques quelconques. La dimension élevée de ces modèles pose des problèmes de stockage, lorsque l'on cherche à les distribuer à grande échelle. Nous proposons ici une technique de compression (avec perte) très efficace de CLUTs 3D, fondée sur un schéma de reconstruction par diffusion anisotrope multi-échelle. Notre méthode affiche un taux de compression moyen supérieur à 99%, pour une dégradation résultante visuellement indiscernabl

    Classification of Hyperspectral Images as Tensors Using Nonnegative CP Decomposition

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    International audienceA Hyperspectral Image (HSI) is an image that is acquired by means of spatial and spectral acquisitions, over an almost continuous spectrum. Pixelwise classification is an important application in HSI due to the natural spectral diversity that the latter brings. There are many works where spatial information (e.g., contextual relations in a spatial neighborhood) is exploited performing a so-called spectral-spatial classification. In this paper, the problem of spectral-spatial classification is addressed in a different manner. First a transformation based on morphological operators is used with an example on additive morphological decomposition (AMD), resulting in a 4-way block of data. The resulting model is identified using tensor decomposition. We take advantage of the compact form of the tensor decomposition to represent the data in order to finally perform a pixelwise classification. Experimental results show that the proposed method provides better performance in comparison to other state-of-the-art methods
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